
Omega 3- Introduction Type, Sources, benefits
What exactly is Omega 3? Let’s find out its types, sources and science behind these essential fatty acids
Significance of Omega 3 in the current scenario
Obesity is a worldwide disease known to affect majority of people and the main reason behind high-risk obesity in men and women is accumulation of SFA or saturated fatty acids in the cells causing lipotoxic damage. But, not all fats are unhealthy; we have a wide range of poly unsaturated fatty acids with multiple physiological advantages. Moreover, in contrast to saturated fatty acids, monounsaturated fatty acids as well as polyunsaturated fatty acids have been reported to neutralize SFA induced cellular damage (Liu et al., 2023). The 2 major classes of these fatty acids are the omega 3 and omega 6. Let’s understand where these names come from, diving deep into organic chemistry. PUFAs consist of long chains of carbon atoms and are usually differentiated from saturated or MUFA (monounsaturated fatty acids) by the presence of 2 or more double bonds between the carbons present in the fatty acid chain. Omega 3 has a C-C double bond and thus often referred to as n-3s while Omega -6 fatty acids have a C-C bond which is 6 carbon atoms away from the methyl end of the fatty acid chain and hence this nomenclature. These omega 3 fatty acids could be further differentiated into alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) where ALA has 18 carbon atoms while EPA + DHA are considered long chain omega 3s as EPA has 20 carbon atoms while DHA has 22.
The Omega 6: Omega 3 ratio
One such important concept is the omega 6: omega 3 ratio. The amount of omega 3 needs to be higher than omega 6 for overall health benefits. An imbalance in the omega 6: omega 3 ratio promotes the pathogenesis of various disorders like cardiovascular diseases and cancer. In scientific language, consumption of high Omega 6 sources increases the rate of conversion of linoleic acid to arachidonic acid resulting in inflammation. On the contrary Omega 3s alone causes improvement in many physiological responses involving the arteries, blood and heart improving cardiovascular health elevating overall health outcomes. High amounts of PUFA leads to high omega6-omega 3 ratio mainly found in western diets where the ratio is usually 15:1. Moreover, studies show that currently the diet of most people contain omega 6 rich food and the consumption of food rich in omega 3 are lowest calling for external supplementation through heart health supplements as well as brain health supplements. Omega 6 intake should be reduced as they are pro-inflammatory while omega 3 s are anti-inflammatory and should be incorporated more for a balanced meal.
Omega 3 deficiency:
- Sensitive, dry skin with unusual increase in acne
- Increased skin sensitivity to UV light
- Depression due to lack of neuroprotective and anti-inflammatory effects of Omega 3
- Dry eye syndrome, eye discomfort, disturbances in normal vision
- Osteoarthritis, rheumatoid arthritis, joint pain, stiffness
- Changes in texture, quality, density of hair leading to low hair quality


