March 11, 2026Wellness

Chasing Precision, Choosing powerful Ingredients

The Newedge promise: Witness the power of Shoden Ashwagandha, highest bioavailability with maximized efficacy = quick and consistent health benefits.

Know your ingredients and their extraction

How is extraction of a bioactive linked to its bioavailability?

The power of any ayurvedic product lies in the clarity of its chemical composition. One of the most important steps involve the extraction of bioactive compounds from its original plant/ herb which is in its crude and raw form. In scientific language, bioactives are compounds or substances having biological activity which exhibit positive effects on living organisms. With the rising demand for Ayurvedic and herbal medicines for global primary healthcare, appropriate extraction techniques need to be applied varying in accordance with each company. Furthermore, scientists have come up with multiple protocols entailing extraction of bioactive ingredients for ensuring the effectiveness and efficacy of the products from their parent plants.

OcitumTM Holy Basil: Standardization

The importance of bio actives is important and determines the efficacy of a product., for eg: 35% withanolides in Ashwagandha extract increases the potency and bioavailability of Ashwagandha. In Newedge Optimised Ashwagandha & Holybasil Complex Ocitum™ Holy Basil is standardized to a potent 5% total Ursolic Acid, 5% Eugenol, and 0.5% Rosmarinic Acid. Also referred to as the “Elixir of Life in Ayurvedic knowledge, Holy Basil contains Eugenol, a 1-hydroxy-2-methoxy-4-allylbenzene compound which is the active ingredient, and has the power of regulating brain functions through regulation of voltage gated cation channels and the subsequent release of neurotransmitters. Although Ayurvedic formulations are usually safe as well as effective, adulteration of low-cost materials or generic standardisation processes reduces the quality of the drug. Hence, the standardisation process needs to be fruitful and of highest quality so that the drug retains its potency and effectivity with increased bioavailability.

Why Ursolic and Rosmarinic acid is added to the extraction process?

Scientific studies claims that the presence of phenolic chemicals in Holy Basil extracts increase the antioxidant qualities possessed by the fresh leaves and stems extract. These substances including rosmarinic acid alongside considerable amounts of eugenol play in important role in increasing the antioxidant activity of the Holy basil extract (Arya et al.). The ratio of standardisation further increases the potency and bioavailability of the holy basil extract. Holy basil has been studied for its anti stress activities where the whole plant extracted with methanol, rosmarinic acid, ociglycoside, ursolic and oleanolic acid have been highly useful against chronic variable stress (Chalkual, 2026). Now, let us understand the benefits of Ursolic and Rosmarinic acid present in holy basil. Rosmarinic acid inhibits GABA transaminase, especially 4-aminobutyrate transaminase due to which it has anxiolytic properties. Similarly, Ursolic acid exhibits anti-cancer properties through damage repair which is mediated by vaccinia related kinase or VRK-1 in the lung cancer cells (Arya et al.).